10 Best Hyaluronic Acid Supplements in 2021 and their Benefits

10 Best Hyaluronic Acid Supplements in 2021 and their Benefits
Last updated:

Nowadays, dietary supplement recommendations are a dime a dozen — it’s impossible for a day to go by without hearing about them on social media, commercials, or even from friends and family. No matter what type of lifestyle they may lead, it seems that everyone has at least one supplement they swear by, and can’t help but talk about.

For those who are into skincare, you may have already learned about the hyaluronic acid food diet and hyaluronic acid supplements. Its key ingredient, hyaluronic acid (also called hyaluronan) has long been used in topical serums, eye drops, and injections. But because of its potent benefits, many people now take hyaluronic acid pills and hyaluronic acid tablets as a supplement.

To know whether hyaluronic acid supplements are certainly beneficial to your health (and not just another flitting fad), let’s first examine the evidence on the supposed benefits of hyaluronic acid supplements, and take a look at some of the best hyaluronic acid supplements 2020. It’s also best to know what is the recommended hyaluronic acid supplements dosage, and whether there are hyaluronic acid supplements side effects we should be wary about.

What is Hyaluronic Acid?

Hyaluronic acid is a polysaccharide (a type of carbohydrate) that is naturally present in the human body. This substance is found in the highest concentrations in the skin, eyes and joints, where it provides lubrication and supports tissue hydration. In addition, it also affects the way the body responds to injury.

As we get older, our hyaluronic acid levels decrease, so hyaluronic acid supplements can help fill in the gap and prevent ageing-related health conditions.

Although it’s a naturally-occurring compound, the hyaluronic acid that is used as medicine and as hyaluronic acid supplements are mostly synthesized forms — these may be made by bacteria in the laboratory or extracted from rooster combs.

How Much Hyaluronic Acid Do We Need?

By now, you may already be wondering whether your diet is deficient in hyaluronic acid (you may also want to check out our article about the diet for acne) and whether you need to take some hyaluronic acid capsules ASAP. But before you spend any minute in futile worry, we’re here to tell you this: there are no universal guidelines for the appropriate use nor the hyaluronic acid supplements dosage.

And this may lead to your next question: what are the types of foods high in hyaluronic acid?

According to the International Journal of Aging and Clinical Research, foods containing hyaluronic acid include the whole bodies of fish, including mackerel, sea bream, and eel. It’s also found on the cartilaginous tissues of beef, pork and poultry. In addition, it’s also not surprising that the highest concentration of hyaluronic acid is found in the eyes and joints of these animals.

If you’re vegetarian, neither is there a need to worry — you can chow on plant-based sources of hyaluronic acid such as fermented soybeans, leafy greens, avocados, carrots, bell peppers, potatoes,  and nuts.

Nonetheless, if you’re not much of a fan of these types of food (especially of animal eyes and joints!), or if you find it hard to consistently monitor the hyaluronic acid levels in your food intake, it might be much more convenient for you to just take hyaluronic acid supplements.

Benefits of Hyaluronic Acid Supplements

10 Best Hyaluronic Acid Supplements in 2021 and their Benefits
Photo Credit: Verywell/Nusha Ashjaee

People take hyaluronic acid pills or hyaluronic acid tablets for a  variety of uses, which include:

1. Hyaluronic Acid Supplements for Skin

Because almost half of the hyaluronic acid in our body is present in our skin, this part benefits the most with our intake of hyaluronic acid supplements.

Hyaluronic acid binds to water to help retain moisture on the skin, so it helps the skin to look and feel more supple. Research also suggests that hyaluronic acid supplements can be an effective aid to reduce wrinkles, redness, and dermatitis.

2.Hyaluronic Acid Supplements for Joints

Keeping the space between your bones well lubricated, hyaluronic acid is also found in the joints. 

When the joints are not properly lubricated, the bones are more likely to grind against each other and cause uncomfortable pain. This is why hyaluronic acid supplements are used in the treatment of people suffering from osteoarthritis, a type of disease caused by wear and tear on the joints over time.

Do Hyaluronic Acid Supplements Really Work?

While all these benefits may seem impressive, the effects of hyaluronic acid supplements for skin has been tested in various research, and the results are quite promising.

Among these is a 2014 study that proved taking hyaluronic acid supplements daily for at least one month can significantly increase skin moisture and reduce dry skin in adults. In this study, the participants were given daily doses of either 120 mg or 240 mg. After comparing the results to the placebo group, researchers concluded that consuming hyaluronic acid moisturizes the skin and hyaluronic acid supplements can make the skin healthy.

The moisturising property and high water retention capacity of hyaluronic acid were further explored in another research, this time published in 2017. Here, researchers studied 60 Japanese male and female subjects aged 22–59 years who had crow’s feet wrinkles. They were given either hyaluronic acid supplements with a rate of 120 mg/day, or a placebo for 12 weeks. After 8 weeks of ingestion, the hyaluronic acid group showed significantly diminished wrinkles compared with the placebo group.

Meanwhile, when it comes to the benefits of hyaluronic acid supplements for joints, more research may be needed.

Nonetheless, there have been several studies that show hyaluronic acid supplements can significantly reduce knee pain in people with osteoarthritis. One of these is Japanese research that studied 60 osteoarthritic subjects who were also randomly assigned to hyaluronic acid supplements or a placebo.  Those who were given 200 mg of hyaluronic acid supplements (once a day every day for 12 months) showed an obvious improvement, especially with the subjects aged 70 years or less. 

What are Some Hyaluronic Acid Supplements Side Effects?

After learning of its excellent hydration and lubrication benefits, hyaluronic acid supplements may now seem too good to be true. At this point, you may be wondering, what are the hyaluronic acid supplements side effects?

Well, here are more reasons to love those hyaluronic acid tablets and hyaluronic acid capsules — they are generally very safe to use, and allergic reactions are very rare. This is because our body naturally produces hyaluronic acid, there are only a few reported side effects.

In fact, in the study of osteoarthritic subjects we’ve discussed above, there were no reported negative side effects in the participants. One thing to note though is that the effects of hyaluronic acid supplements during pregnancy or breastfeeding have not been thoroughly studied. As such, pregnant or breastfeeding women should be cautious, or better yet, avoid supplementing with it.

Evidence has also been found that cancer cells are sensitive to hyaluronic acid, so taking hyaluronic acid supplements might make them grow faster. Therefore, it’s not advisable for people with cancer or a history of cancer to ingest hyaluronic acid supplements.

What to Look for in a Hyaluronic Acid Supplement

  • Hyaluronic Acid Supplements Dosage – There are some hyaluronic acid supplement manufacturers who recommend a dose of 200-milligram (mg) per day, while others endorse up to 1,000 mg daily. That said, there is no sufficient evidence that higher doses of hyaluronic acid achieve better results. In fact, this clinical study achieved results with a limited daily intake of 120–240 mg of hyaluronic acid supplement for its participants.
  • Collagen with Hyaluronic Acid Supplements – Some collagen supplements include complimentary ingredients such as hyaluronic acid. By working together, these two promotes optimal skin moisture since collagen is the protein providing your skin with structure.

Review of Top 10 Hyaluronic Acid Supplements in Amazon

There are so many brands and formulations of hyaluronic acid supplements out there, and not all of us have the time to pore over the countless hyaluronic acid supplements reviews. So before you get lost in the labyrinth of choices for hyaluronic acid tablets and hyaluronic acid pills, let’s look at the top performers first. 

When it comes to the trusted brands and top-selling HA products in Amazon, here are the best hyaluronic acid supplements 2020:

1. OLLY Collagen Gummy Rings

10 Best Hyaluronic Acid Supplements in 2021 and their Benefits10 Best Hyaluronic Acid Supplements in 2021 and their Benefits

Chew your way to a moisturised, healthy skin with OLLY Collagen Gummy Rings. They’re both delicious (naturally flavoured Peach Bellini with no artificial colours or flavours) and delightful (just like eating gummies, no food or water needed).

It’s among the best hyaluronic acid supplements 2020 because they’re packed with collagen—a beauty essential that’s essential for that youthful glow. Aside from hyaluronic acid, OLLY Collagen Gummy Rings deliver a clinically-tested dose (2.5 grams) of Bioactive Collagen Peptides. As collagen with hyaluronic acid supplements, they’ve been shown to support collagen production, boost skin elasticity and reduce the appearance of worrisome wrinkles in as little as 4 weeks. With all these hyaluronic acid supplements benefits, it’s a 9/10 for us!

View these hyaluronic acid supplements on Amazon.

2. NatureBell Hyaluronic Acid Supplements 

10 Best Hyaluronic Acid Supplements in 2021 and their Benefits10 Best Hyaluronic Acid Supplements in 2021 and their Benefits

NatureBell Hyaluronic Acid Supplements come with  25 mg vitamin C per serving, ensuring that these hyaluronic acid capsules can help reduce the signs of ageing in the skin. As hyaluronic acid helps keep the skin moisturised, while vitamin C protects it from sun damage and can help fade skin discolouration. As one of the best hyaluronic acid supplements 2020, not only does NatureBell Hyaluronic Acid Supplements support the hydration of skin, but of the hair and nails.  Another 9/10 for these hyaluronic acid capsules!

View these hyaluronic acid capsules on Amazon.

3. Amazing Formulas Hyaluronic Acid 100 mg 120 Capsules 

10 Best Hyaluronic Acid Supplements in 2021 and their Benefits10 Best Hyaluronic Acid Supplements in 2021 and their Benefits

Non-GMO and gluten-free, Amazing Formulas Hyaluronic Acid Capsules can fit in most diet plans — they’re free of fish, eggs, fish, peanuts, milk, soy, tree nuts and wheat.

These hyaluronic acid capsules provide a 100 mg dosage of hyaluronic acid which is already an optimum dosage to reap its benefits. It’s one of the best hyaluronic acid supplements 2020 that’s known to enhance the health of the skin, support healthy joints and connective tissue. Get the straightforward hyaluronic acid supplements benefits through this product: 8/10!

View these hyaluronic acid capsules on Amazon.

4. NOW Supplements Hyaluronic Acid 

10 Best Hyaluronic Acid Supplements in 2021 and their Benefits10 Best Hyaluronic Acid Supplements in 2021 and their Benefits

Also coming to you with a 100 mg dosage of hyaluronic acid, NOW Supplements Hyaluronic Acid combines the power of L-proline, alpha-lipoic acid, and grape seed extract to create a more complete formula.

These hyaluronic acid capsules are also soy-free, sugar-free, non-GMO, vegan/vegetarian, nut-free, made without gluten, dairy-free, egg-free, Kosher, and low in sodium. It’s an 8.5/10 for us!

View these hyaluronic acid capsules on Amazon.

5. Jarrow Formulas Hyaluronic Acid

10 Best Hyaluronic Acid Supplements in 2021 and their Benefits10 Best Hyaluronic Acid Supplements in 2021 and their Benefits

With a slightly higher 120 mg per serving Jarrow Formulas Hyaluronic Acid capsules further ensure that your body makes use of HA by using fermented, and low molecular weight hyaluronic acid.

This increased bioavailability makes it the ultimate skin optimizer — it’s no wonder it’s counted among Amazon’s Choice for best hyaluronic acid supplements 2020. We rate it 9/10 too!

View these hyaluronic acid capsules on Amazon.

6. Horbäach Hyaluronic Acid Capsules 

10 Best Hyaluronic Acid Supplements in 2021 and their Benefits10 Best Hyaluronic Acid Supplements in 2021 and their Benefits

Horbäach Hyaluronic Acid Capsules offers a 200 mg dosage of HA to encourage a radiant, smooth, and youthful complexion. These hyaluronic acid capsules are also gluten-free, non-GMO, and lactose-free, making them one of the best hyaluronic acid supplements 2020. This is your option if you believe you need a higher hyaluronic acid supplements dosage. We think it’s an 8/10!

View these hyaluronic acid capsules on Amazon.

7. Schiff Glucosamine With Hyaluronic Acid 

10 Best Hyaluronic Acid Supplements in 2021 and their Benefits10 Best Hyaluronic Acid Supplements in 2021 and their Benefits

Glucosamine helps maintain the healthy structure and function of cartilage in your joints. So if you’re primarily concerned about hyaluronic acid supplements for joints, then this could be the best hyaluronic acid supplements 2020 for you. Paired with HA, these hyaluronic acid supplements from Schiff can definitely support joint lubrication and smooth movement. For this, we think it’s an 8/10 as well!

View these hyaluronic acid supplements on Amazon.

8. Ultimate H.A. Formula 

10 Best Hyaluronic Acid Supplements in 2021 and their Benefits10 Best Hyaluronic Acid Supplements in 2021 and their Benefits

What’s ultimate about the Ultimate H.A. Formula is that these hyaluronic acid supplements contain a clinically tested ingredient, BioCell Collagen — which they provide in the exact amount used (1000 mg) in clinical research and testing for skin health.

Its 100 mg of hyaluronic acid, along with a patented combination of hydrolyzed collagen type II, and chondroitin sulfate actively promote skin and joint collagens. We believe that as one of the best hyaluronic acid supplements 2020, this collagen with hyaluronic acid supplements deserves an 8.5/10!

View these hyaluronic acid supplements on Amazon.

9. HUM Glow Sweet Glow 

10 Best Hyaluronic Acid Supplements in 2021 and their Benefits10 Best Hyaluronic Acid Supplements in 2021 and their Benefits

There’s just something precious with vegan tangerine-flavoured gummy hearts — and it’s HUM Glow Sweet Glow’s advanced formulation of hyaluronic acid, vitamin C and vitamin E. This powerful combination can help lock moisture to the skin and boost hydration, keep skin plump and glowing, and stimulate collagen production. It also doesn’t hurt that they’re free of artificial colours, flavours and preservatives. An 8.5 is in order for these hyaluronic acid supplements!

View these hyaluronic acid supplements on Amazon.

10. NeoCell Hyaluronic Acid Berry Liquid  

10 Best Hyaluronic Acid Supplements in 2021 and their Benefits10 Best Hyaluronic Acid Supplements in 2021 and their Benefits

If you think hyaluronic acid supplements are all in hyaluronic acid capsules and tablets, we’ve got a liquid option for you.

NeoCell Hyaluronic Acid Berry Liquid lets you drink your daily dose of HA and offers antioxidant support through vitamin C in its formulation— providing support from free radicals and promoting cellular health.  We also think it deserves its spot among the best hyaluronic acid supplements 2020, so we give it an 8/10!

View these hyaluronic acid supplements on Amazon.

Find the Right Hyaluronic Acid Supplements for You

With so many hyaluronic acid supplements benefits and very few side effects, it’s time to find the right product that works for you. Keep in mind that at this time, there is no sufficient evidence to say that that higher doses of hyaluronic acid are better. A daily intake of 120–240 mg (the hyaluronic acid supplements dosage used in studies) is recommended as you look at brands and formulations of hyaluronic acid supplements in the market today.

With these hyaluronic acid supplements reviews, you’re now better informed as you take a step towards healthy skin, hair and joints!